Chronic stress is a known accelerator of the aging process, but combining lifestyle changes with NMN might offer a way to mitigate these effects, promoting a longer life.
Stress and Aging
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Telomere Shortening: Stress can accelerate telomere attrition, a marker of biological aging. Epel et al. (2004) in Proceedings of the National Academy of Sciences showed how stress affects telomere length (link).
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Inflammation: Chronic stress leads to systemic inflammation, a contributor to aging and disease. Kiecolt-Glaser et al. (2003) in Psychosomatic Medicine linked stress to increased inflammation (link).
NMN's Role in Stress Management
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Cellular Resilience: NMN increases NAD+, which supports cells under stress, potentially extending cellular life. Imai & Guarente (2014) discuss NAD+'s role in stress response and aging (link).
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Sirtuin Activation: These proteins can mitigate stress at a cellular level by repairing DNA and reducing oxidative damage. Haigis & Sinclair (2010) in Annual Review of Pathology review sirtuins' functions in stress resistance (link).
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Mental Health: By supporting brain health, NMN might help with stress resilience, potentially reducing the impact of stress on cognitive function. Yoshino et al. (2018) in Cell Metabolism hinted at NMN's neuroprotective effects (link).
Practical Application
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Stress Management Techniques: Include mindfulness, meditation, and yoga in your routine to manage stress levels.
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NMN Supplementation: Regular NMN intake (e.g., 250-500 mg daily) might bolster your body's response to stress. The exact timing isn't critical, but consistency is key.
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Lifestyle Adjustments: Ensure adequate rest, nutrition, and social support to complement NMN's stress-fighting capabilities.
While lifestyle changes are paramount for managing stress, NMN could provide an additional layer of defense against the aging effects of stress by supporting cellular health and resilience. This combination might not only extend life but improve the quality of those years by reducing stress's toll on the body and mind.
